Mathilde Pohin

Postdoctoral Research Scientist

Leukocytes -stromal interaction in IBD

After completing a PhD in cellular and molecular immunology in the University of Poitiers (France), I joined the Kennedy Institute of Rheumatology in November 2017.

My research aims to understand the function of stromal cells in IBD and how these cells interact with immune cells to sustain chronic inflammation. I am dissecting the cellular and molecular landscape of inflamed tissue from IBD patients with gene expression profiling, quantitative in situ analyses, multiplexed image fluorescence and functional ex vivo assays. I am also using in vivo mouse models of IBD to interrogate key pathways involved in IBD pathophysiology. and identify new therapeutic targets.